Mouse hepatic stellate cell line

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August undefined, 2024

Nettet19. apr. 2024 · Hepatic stellate cells (HSCs) are specialized pericyte-like cells, located in the space of Disse, that wrap liver sinusoids [ 1] and interact with both hepatocytes and liver sinusoidal endothelial cells [ 2 … Nettet26. mai 2016 · Objective: Our aim was to establish a correlation between hepatic stellate cells (HSCs) activity within different areas of hepatic tissue and the degree of liver fibrosis,...

Activated Hepatic Stellate Cells Promote the M1 to M2 …

NettetActivated hepatic stellate cells are a major cellular source of MCP-1 in injured livers . In line with this, the expression of α-smooth muscle actin ( α-sma ), a marker for HSC … Nettet8. okt. 2013 · The murine cell line GRX has been introduced as an experimental tool to study aspects of hepatic stellate cell biology. It was established from livers of C3H/HeN mice that were infected with ... cards for nursing homes

Human Pancreatic Stellate Cells - ScienCell Research Laboratories

NettetIn this study, we used the human hepatic stellate cell line LX-2 and the classical CCl4-induced hepatic fibrosis mouse model for in vitro and vivo experiments. We found that eupatilin significantly repressed the levels of the fibrotic markers COL1α1 and α-SMA, as well as other collagens in LX-2 cells. Nettet29. mai 2024 · Immortalized hepatic stellate cells (HSCs) established from mouse, rat, and humans are valuable in vitro models for the biomedical investigation of liver biology. These cell lines are homogenous, thereby providing consistent and reproducible results. They grow more robustly than primary HSCs and provide an unlimited supply of … Nettet12. apr. 2024 · Experiments were performed in wild-type and FNDC5 −/− mice, primary mouse HSCs, and human hepatic stellate cell line (LX2). Mice were treated with carbon tetrachloride (CCl 4) or bile duct ligation (BDL) to induce liver fibrosis. EVs derived from HSCs were purified and injected intraperitoneally into mice. cards for next day delivery

Insights into the impact of hepatitis B virus on hepatic stellate cell ...

Mouse hepatic stellate cell line

HSC-T6 Rat Hepatic Stellate Cell Line The HSC-T6 rat hepatic stellate ...

NettetHepatic stellate cells (HSCs) are the primary extracellular matrix-producing cells within the liver and have numerous vital functions. A robust protocol for the isolation and … Nettet10. mai 2024 · Activation of hepatic stellate cells (HSCs) in liver injury is the primary driver of hepatic fibrosis. In this Review, Tsuchida and Friedman detail the varied …

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NettetSCC064 Sigma-Aldrich LX-2 Human Hepatic Stellate Cell Line Download Zoom The LX-2 human hepatic stellate cell line has been extensively characterized and retain key features of hepatic stellate cytokine signaling, neuronal gene expression, retinoid metabolism, and fibrogen More>> Nettet3. apr. 2024 · Materials and methods. ICR mice with CCl 4-induced hepatic fibrosis were supplemented with Sch B (40 mg/kg) for 30 d and LX2 cells were treated with Sch B (5, 10 and 20 μM) for 24 h.Cellular senescence was assessed by senescence-related indicators senescence-associated β-galactosidase (SA-β-gal) activity and the expression of p16, …

NettetMethods: Experiments were performed in wild-type and FNDC5-/-mice, primary mouse HSCs, and human hepatic stellate cell line (LX2). Mice were treated with carbon … NettetProtein expression of arginine catabolizing enzymes. In line with the mRNA levels, the protein level of iNOS was increased at Day 1 but strongly reduced at Day 7 (Figure 2A,C).Protein expression of Arg1 was increased at Day 3 and appeared to be even more increased at Day 7 (Figure 2A,C).As expected, protein levels of the activation markers …

Nettet4. des. 2016 · High yield and high purity isolation of hepatic stellate cells from normal and fibrotic mouse liver - Co 1.77 MB Hepatic Stellate Cells Hematopoietic Stem Cells Stem Cell... NettetFor reasons that are not entirely known, males may be three to five times more likely than females to develop HCC, the most common type of liver cancer. 83% of cases are diagnosed in less-developed countries, with the highest rates found in east and southeast Asia and in middle and western Africa; rates are lower in south-central and western Asia.

Nettet4. okt. 2024 · Mouse hepatocyte cell line AML12 was purchased from the Chinese Academy of Sciences (Shanghai, China) and cultured in AML12 specific culture medium (Procell, Wuhan, China). Mouse hepatic stellate cell (CP-M041) was purchased from Procell (Wuhan, China) and maintained in specific hepatic stellate cell medium (CM …

NettetMethods: Experiments were performed in wild-type and FNDC5-/-mice, primary mouse HSCs, and human hepatic stellate cell line (LX2). Mice were treated with carbon tetrachloride (CCl 4) or bile duct ligation (BDL) to induce liver fibrosis. EVs derived from HSCs were purified and injected intraperitoneally into mice. brookdale battle creek miNettet29. mai 2024 · Immortalized hepatic stellate cells (HSCs) established from mouse, rat, and humans are valuable in vitro models for the biomedical investigation of liver … cards for parts workNettetThe HSC-T6 rat hepatic stellate cell line is a valuable cell model for studies of retinoid metabolism based on their similar retinoid phenotype as primary cells. Synonym (s): HSC, Perisinusoidal cells, Ito cells, Hepatic lipocytes, Hepatic pericytes eCl@ss: 32011203 NACRES: NA.81 Pricing and availability is not currently available. Properties brookdale canyon lakes kennewick